Br-C3-methyl ester |
カタログ番号GC60660 |
Br-C3-メチルエステルは、PROTAC PD-1/PD-L1 degrader-1 の合成に使用できるアルキル/エーテルベースの PROTAC リンカーです。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 4897-84-1
Sample solution is provided at 25 µL, 10mM.
Br-C3-methyl ester is a Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTAC PD-1/PD-L1 degrader-1[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[1]. Binbin Cheng, et al. Discovery of novel resorcinol diphenyl ether-based PROTAC-like molecules as dual inhibitors and degraders of PD-L1. Eur J Med Chem. 2020;199:112377.
Average Rating: 5
(Based on Reviews and 8 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *