CAY10565 (Synonyms: 4(pmethoxyphenyl)1,3,2Oxathiazolylium5olate) |
| カタログ番号GC43170 |
S-ニトロソチオール（RSNO）は、内因性および外因性の一酸化窒素（NO）ドナーとして機能する分子のクラスです。
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Sample solution is provided at 25 µL, 10mM.
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S-Nitrosothiols (RSNOs) are a class of molecules that function as exogenous and endogenous nitric oxide (NO) donors. RSNOs found in vivo include proteins such as S-nitrosohemoglobin and S-nitrosoalbumin, as well as low molecular weight species such as S-nitrosoglutathione (GSNO) and S-nitrosocysteine (CysNO). CAY10565 is a member of a new class of S-nitrosothiol species that act as NO donors under acidic conditions. It decomposes with a half-life of 130 minutes in 0.1 M phosphate buffer, pH 5.0, at 37°C and relaxes phenylephrine-constricted rat aortic strips 71% and 44% at pH 6.0 and 7.4, respectively.
Average Rating: 5 (Based on Reviews and 7 reference(s) in Google Scholar.)
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