Diflorasone Diacetate (Synonyms: U-34865) |
カタログ番号GC40867 |
ジフロラゾン ジアセテートは、局所または局所剤として使用される抗炎症性ステロイド化合物です。
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Cas No.: 33564-31-7
Sample solution is provided at 25 µL, 10mM.
Diflorasone is a corticosteroid with anti-inflammatory activity. It reduces production of the inflammatory cytokines Il-6, Il-4, and macrophage inflammatory protein-2 (Mip-2) and completely inhibits swelling in the ears of toluene-2,4-diisocyaniate-sensitized mice following topical administration of 20 µL of a 0.05% solution. Diflorasone inhibits RANTES and thymus and activation regulated chemokine (TARC) in a dinitrochlorobenzene-induced mouse model of allergic contact dermatitis. It also inhibits proliferation of human keratinocytes in vitro and reduces epidermal thickening in a mouse model of psoriasis induced by imiquimod .
Average Rating: 5
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