DprE1-IN2 |
| カタログ番号GC18263 |
DprE1-IN2 (化合物 18) は、28 nM の IC50 を持つ強力な DprE1 阻害剤です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1615713-87-5
Sample solution is provided at 25 µL, 10mM.
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DprE1-IN-2 (compound 18) is a potent DprE1 inhibitor with an IC50 of 28 nM. DprE1-IN-2 has antituberculosis effect[1].
DprE1-IN-2 (compound 18; oral; 100 mg/kg) has t1/2 of 0.9 hours and Cmax of 70 μM in BALB/c Mice[1].
References:
[1]. Shirude PS et al. Lead optimization of 1,4-azaindoles as antimycobacterial agents. J Med Chem. 2014 Jul 10;57(13):5728-37.
Average Rating: 5 (Based on Reviews and 25 reference(s) in Google Scholar.)
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