Ethyl Orsellinate (Synonyms: NSC 149781) |
カタログ番号GC40699 |
オルセリン酸エチルは、地衣類の代謝産物であり、抗増殖活性と抗腫瘍活性を持つレカノール酸の誘導体です。
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Cas No.: 2524-37-0
Sample solution is provided at 25 µL, 10mM.
Ethyl orsellinate is a lichen metabolite and a derivative of lecanoric acid that has antiproliferative activities. It inhibits the proliferation of human Hep-2 larynx carcinoma, MCF-7 breast cancer, and 786-0 kidney carcinoma cells, as well as B16-F10 murine melanoma and non-cancerous Vero cells (IC50s = 31.2, 70.3, 47.5, 64.8, and 28.1 µg/ml, respectively). Ethyl orsellinate is toxic to brine shrimp (A. salina) with an LC50 value of 495 µM.
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