Extracellular Death Factor (Synonyms: EDF) |
カタログ番号GC43645 |
細菌におけるプログラムされた細胞死は、クオーラムセンシングと呼ばれる細胞間通信のシステムに依存しています。
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Cas No.: 960129-66-2
Sample solution is provided at 25 µL, 10mM.
Programmed cell death in bacteria is dependent on a system of cell-to-cell communication termed quorum sensing. Extracellular death factor (EDF) is a linear pentapeptide that communicating cells produce and release, which upon reaching a sufficient concentration activates the cell death pathway in a subset of cells. It is sensitive to extreme pH, high temperatures, and other stressful conditions. At 2.5 ng/ml, EDF has been shown to facilitate mazEF-mediated cell death, significantly reducing population size in E. coli cultures.
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