Feprazone |
カタログ番号GC40565 |
フェニルブタゾンの類似体であるフェプラゾン (DA2370; プレナゾン) は、鎮痛作用と解熱作用を持つ非ステロイド性抗炎症剤です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 30748-29-9
Sample solution is provided at 25 µL, 10mM.
Feprazone is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor that is 10-fold selective for COX-2 over COX-1. It reduces LPS-induced prostaglandin E2 production in bovine arterial endothelial cells (IC50 = 1 μM). Oral administration of feprazone (25-100 mg/kg) reduces vascular permeability, edema, and nociception in a rat model of adjuvant-induced arthritis.
Average Rating: 5
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