Filastatin |
| カタログ番号GC60841 |
フィラスタチンは、カンジダ・アルビカンスのフィラメント形成の長期にわたる阻害剤です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 431996-53-1
Sample solution is provided at 25 µL, 10mM.
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Filastatin is a long-lasting inhibitor of Candida albicans filamentation. Filastatin inhibits adhesion by multiple pathogenic Candida species with an IC50 of ~3 μM in the GFP-based adhesion assay. Filastatin inhibits fungal adhesion to polystyrene and human cells, the yeast-to-hyphal morphological transition, induction of the hyphal-specific HWP1 promoter. Filastatin has potent antifungal effect[1].
[1]. Ahmed Fazly, et al. Chemical screening identifies filastatin, a small molecule inhibitor of Candida albicans adhesion, morphogenesis, and pathogenesis. Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13594-9.
Average Rating: 5 (Based on Reviews and 12 reference(s) in Google Scholar.)
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