Crebanine (Synonyms: (–)-Crebanine) |
| カタログ番号GC35747 |
Stephania venosa 由来のアルカロイドであるクレバニンは、ヒト癌細胞の G1 停止とアポトーシスを誘導します。
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Cas No.: 25127-29-1
Sample solution is provided at 25 µL, 10mM.
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Crebanine, an alkaloid from Stephania venosa, induces G1 arrest and apoptosis in human cancer cells. Crebanine exhibits anti-inflammatory activity via suppressing MAPKs and Akt signaling. Crebanine also possesses antiarrhythmic effect[1][2].
[1]. Wongsirisin P, et al. Induction of G1 arrest and apoptosis in human cancer cells by crebanine, an alkaloid from Stephania venosa. Chem Pharm Bull (Tokyo). 2012;60(10):1283-9. [2]. Intayoung P, et al. Antiinflammatory Activities of Crebanine by Inhibition of NF-κB and AP-1 Activation through Suppressing MAPKs and Akt Signaling in LPS-Induced RAW264.7 Macrophages. Biol Pharm Bull. 2016;39(1):54-61.
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