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Cycloguanil

カタログ番号GC35780

プログアニルの活性代謝物であるシクログアニルは、赤血球と肝細胞のマラリアシゾントに作用します。

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Cycloguanil 化学構造

Cas No.: 516-21-2

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Cycloguanil, the active metabolite of Proguanil, acts on malaria schizonts in erythrocytes and hepatocytes[1].

[1]. Matthaei J, et al. OCT1 Deficiency Affects Hepatocellular Concentrations and Pharmacokinetics of Cycloguanil, the Active Metabolite of the Antimalarial Drug Proguanil. Clin Pharmacol Ther. 2019 Jan;105(1):190-200.

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