Fulvestrant S enantiomer |
カタログ番号GC36089 |
フルベストラント S エナンチオマー (ICI 182780 S エナンチオマー) は、フルベストラントの S エナンチオマーです。フルベストラントは、9.4 nM の IC50 を持つ強力なエストロゲン受容体アンタゴニストです。
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Cas No.: 1316849-17-8
Sample solution is provided at 25 µL, 10mM.
Fulvestrant S enantiomer is the S enantiomer of Fulvestrant. Fulvestrant is a selective estrogen receptor (ER) antagonist which can be used to treat breast cancer.
[1]. Caprioglio D, et al. An alternative synthesis of the breast cancer drug fulvestrant (Faslodex•): catalyst control over C-C bond formation. Chem Commun (Camb). 2015 Oct 14;51(80):14866-8. [2]. Osborne CK, et al. Fulvestrant: an oestrogen receptor antagonist with a novel mechanism of action. Br J Cancer. 2004 Mar;90 Suppl 1:S2-6.
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