HCV-IN-4 |
| カタログ番号GC36213 |
HCV-IN-4 は強力な経口活性 HCV NS5A 阻害剤であり、GT1a、GT2b、GT3a、GT1a Y93H、および GT1a L31V に対して優れた効力を示し、EC90 はそれぞれ 3 pM、0.3 nM、0.01 nM、0.5 nM、および 0.02 nM です。 。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2058080-25-2
Sample solution is provided at 25 µL, 10mM.
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HCV-IN-4 is a potent and orally active HCV NS5A inhibitor, shows great potency against GT1a, GT2b, GT3a, GT1a Y93H and GT1a L31V, with EC90s of 3 pM, 0.3 nM, 0.01 nM, 0.5 nM and 0.02 nM, respectively[1]. EC90: 3 pM (GT1a), 0.3 nM (GT2b), 0.01 nM (GT3a), 0.5 nM (GT1a Y93H), 0.02 nM (GT1a L31V)[1]
[1]. Yu W, et al. Discovery of Chromane Containing Hepatitis C Virus (HCV) NS5A Inhibitors with Improved Potency against Resistance-Associated Variants. J Med Chem. 2016 Nov 23;59(22):10228-10243. Epub 2016 Nov 9.
Average Rating: 5 (Based on Reviews and 13 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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