Hydrolyzed Fumonisin B1 (Synonyms: Aminopentol) |
| カタログ番号GC36270 |
加水分解フモニシン B1 (アミノペントール) は、マイコトキシン フモニシン B1 の骨格であり、主要な加水分解生成物です。
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Cas No.: 145040-09-1
Sample solution is provided at 25 µL, 10mM.
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Hydrolyzed Fumonisin B1 (Aminopentol) is the backbone and main hydrolysis product of the mycotoxin fumonisin B1 (FB1), can weakly inhibit ceramide synthase[1].
[1]. Collins TF, et al. Effects of aminopentol on in utero development in rats. Food Chem Toxicol. 2006 Feb;44(2):161-9. [2]. Humpf HU, et al. Acylation of naturally occurring and synthetic 1-deoxysphinganines by ceramide synthase. Formation of N-palmitoyl-aminopentol produces a toxic metabolite of hydrolyzed fumonisin, AP1, and a new category of ceramide synthase inhibitor. J Biol Chem. 1998 Jul 24;273(30):19060-4. [3]. Schmelz EM, et al. Induction of apoptosis by fumonisin B1 in HT29 cells is mediated by the accumulation of endogenous free sphingoid bases. Toxicol Appl Pharmacol. 1998 Feb;148(2):252-60.
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