Macropa-NH2 hydrochloride |
カタログ番号GC36527 |
Macropa-NH2 塩酸塩は、Macropa-NCS の前駆体です。 Macropa-NCS は、抗ヒト HER2 および前立腺特異的膜抗原標的化合物 RPS-070 に結合しており、軟部組織転移の治療に適用される有望な治療用放射性核種です。
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Cas No.: 2443966-86-5
Sample solution is provided at 25 µL, 10mM.
Macropa-NH2 hydrochloride is the precursor of Macropa-NCS. Macropa-NCS is conjugated to trastuzumab as well as to the prostate-specific membrane antigen-targeting compound RPS-070 and is a promising therapeutic radionuclide applied in the treatment of soft-tissue metastases[1][2].
[1]. Thiele NA, et al. An Eighteen-Membered Macrocyclic Ligand for Actinium-225 Targeted Alpha Therapy. Angew Chem Int Ed Engl. 2017 Nov 13;56(46):14712-14717. [2]. Thiele NA, et al. An Eighteen-Membered Macrocyclic Ligand for Actinium-225 Targeted Alpha Therapy. Angew Chem Int Ed Engl. 2017 Nov 13;56(46):14712-14717.
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