N6-(4-Hydroxybenzyl)adenosine |
| カタログ番号GC36680 |
N6-(4-ヒドロキシベンジル)アデノシンは、コラーゲンによって in vitro で誘導される血小板凝集の阻害剤であり、その活性範囲が実証されました (IC50: 6.77-141 μM)。
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Cas No.: 110505-75-4
Sample solution is provided at 25 µL, 10mM.
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N6-(4-Hydroxybenzyl)adenosine is a inhibitor of platelet aggregation induced in vitro by collagen and their activity range was demonstrated (IC50: 6.77-141 μM). IC50 value: 6.77-141 μMTarget: P2Y12receptorAnti-aggregation activity of N6-(4-Hydroxybenzyl)adenosine could involve an interaction with the P2Y12receptor binding site.
[1]. Vistoli G, et al. Naturally occurring N(6)-substituted adenosines (cytokinin ribosides) are in vitro inhibitors of platelet aggregation: an in silico evaluation of their interaction with the P2Y(12) receptor. Bioorg Med Chem Lett. 2014 Dec 15;24(24):5652-5655.
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