Odiparcil (Synonyms: SB-424323) |
| カタログ番号GC36792 |
Odiparcil (SB-424323) は、経口で活性なベータ-d-チオキシロシド類似体であり、有害な出血イベントのリスクの低減に関連する抗血栓活性を備えています。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 137215-12-4
Sample solution is provided at 25 µL, 10mM.
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Odiparcil (SB-424323) is an orally active beta-d-thioxyloside analog with antithrombotic activity associated with a reduced risk of adverse bleeding events. Odiparcil (SB-424323) is indirect thrombin inhibitor that exerts its anticoagulant effect through activation of antithrombin II (heparin cofactor II) [1][2]. Thrombin[2]
[1]. Myers AL, et al. Characterization of total plasma glycosaminoglycan levels in healthy volunteers following oral administration of a novel antithrombotic odiparcil with aspirin or enoxaparin. J Clin Pharmacol. 2008 Oct;48(10):1158-70 [2]. Levy JH, et al. Novel oral anticoagulants: implications in the perioperative setting. Anesthesiology. 2010 Sep;113(3):726-45.
Average Rating: 5 (Based on Reviews and 29 reference(s) in Google Scholar.)
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