Urolithin B (Synonyms: NSC 94726, 3-hydroxy Urolithin) |
| カタログ番号GC38679 |
ウロリチン B は、エラジタンニンの腸内微生物代謝産物の 1 つで、抗炎症作用と抗酸化作用があります。
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Cas No.: 1139-83-9
Sample solution is provided at 25 µL, 10mM.
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Urolithin B is one of the gut microbial metabolites of ellagitannins, and has anti-inflammatory and antioxidant effects. Urolithin B inhibits NF-κB activity by reducing the phosphorylation and degradation of IκBα, and suppresses the phosphorylation of JNK, ERK, and Akt, and enhances the phosphorylation of AMPK. Urolithin B is also a regulator of skeletal muscle mass[1][2].
[1]. Lee G, et al. Anti-inflammatory and antioxidant mechanisms of urolithin B in activated microglia. Phytomedicine. 2019 Mar 1;55:50-57. [2]. Rodriguez J, et al. Urolithin B, a newly identified regulator of skeletal muscle mass. J Cachexia Sarcopenia Muscle. 2017 Aug;8(4):583-597.
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