GDC-0339 |
カタログ番号GC32958 |
GDC-0339 は強力で、経口で生物学的に利用可能で、忍容性の高い pan-Pim キナーゼ阻害剤であり、Pim1、Pim2、Pim3 の Kis はそれぞれ 0.03 nM、0.1 nM、0.02 nM です。 GDC-0339 は、多発性骨髄腫の潜在的な治療法として発見されました。
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Cas No.: 1428569-85-0
Sample solution is provided at 25 µL, 10mM.
GDC-0339 is a Pim kinase inhibitor with IC50 of 43.6 nM for BaF3 PIM1.IC50 value: 43.6 nM (for BaF3 PIM1), 0.04 nM (Ki, for PIM1 LC-3K)Target: Pim
Review for GDC-0339
Average Rating: 5
(Based on Reviews and 23 reference(s) in Google Scholar.)Review for GDC-0339
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