ICI 211965 (ZM-211965) (Synonyms: ZM-211965) |
| カタログ番号GC31947 |
ICI 211965 (ZM-211965) (ZM-211965) は、選択的かつ経口的に強力な 5-リポキシゲナーゼ (5-LPO) 阻害剤です。
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Cas No.: 129424-08-4
Sample solution is provided at 25 µL, 10mM.
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ICI 211965 is a selective and orally potent 5-Lipoxygenase (5-LPO) inhibitor.
ICI 211965 is a selective and orally potent 5-Lipoxygenase (5-LPO) inhibitor. ICI 211965 reduces the leakage of lactate dehydrogenase (LD) and lipid peroxidation at concentrations related to its antioxidative effect and not to its 5-1ipoxygenase-inhibiting effect[1].
[1]. Crawley GC, et al. Methoxytetrahydropyrans. A new series of selective and orally potent 5-lipoxygenase inhibitors. J Med Chem. 1992 Jul 10;35(14):2600-9.
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