ML188 |
| カタログ番号GC39497 |
クラス初のプローブである ML188 は、IC50 が 1.5 μM の選択的非共有結合 SARS-CoV 3CLpro 阻害剤です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1417700-13-0
Sample solution is provided at 25 µL, 10mM.
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ML188, a first in class probe, is a selective non-covalent SARS-CoV 3CLpro inhibitor with an IC50 of 1.5 μM. Antiviral activity[1].
[1]. Jacobs J, et al. Discovery, synthesis, and structure-based optimization of a series of N-(tert-butyl)-2-(N-arylamido)-2-(pyridin-3-yl) acetamides (ML188) as potent noncovalent small molecule inhibitors of the severe acute respiratory syndrome coronavirus (SARS-CoV) 3CL protease. J Med Chem. 2013 Jan 24;56(2):534-46.
Average Rating: 5 (Based on Reviews and 32 reference(s) in Google Scholar.)
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