N6-Ethyladenosine (Synonyms: NSC 516603) |
| カタログ番号GC34921 |
N6-エチルアデノシンはアデノシン誘導体であり、hA1AR と hA3AR の Kis はそれぞれ 4.9 と 4.7 nM で、アデノシン受容体アゴニストとして機能します 。
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Cas No.: 14357-08-5
Sample solution is provided at 25 µL, 10mM.
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N6-Ethyladenosine is an adenosine derivative, acts as a Adenosine receptor agonist, with Kis of 4.9 and 4.7 nM for hA1AR and hA3AR, respectively[1]. Ki: 4.9 nM (hA1AR), 4.7 nM (hA3AR)[1]
N6-Ethyladenosine (Compound 28) exhibits more selectivity at hA1AR and hA3AR over hA2AR (Ki, 8900±770 nM)[1].
[1]. Kimand SK, et al. Three-dimensional quantitative structure-activity relationship of nucleosides acting at the A3 adenosine receptor: analysis of binding and relative efficacy. J Chem Inf Model. 2007 May-Jun;47(3):1225-33. Epub 2007 Mar 6.
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