Pep 2-8 (Synonyms: TVFTSWEEYLDWV-NH2) |
| カタログ番号GC50447 |
Pep 2-8 は、結合 KD が 0.7 μM、IC50 が 1.4 μM の PCSK9 阻害剤です。
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Cas No.: 1541011-97-5
Sample solution is provided at 25 µL, 10mM.
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Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor. Potent inhibitor of PCSK9 binding to LDL receptor (IC50 = 0.8 μM). Restores LDL uptake in HepG2 cells treated with PCSK9.
Zhang et al (2014) Identification of a small peptide that inhibits PCSK9 protein binding to the low density lipoprotein receptor. J.Biol.Chem. 289 942 PMID:24225950
Average Rating: 5 (Based on Reviews and 8 reference(s) in Google Scholar.)
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