PF-1163B |
| カタログ番号GC44610 |
PF-1163Bは、エルゴステロール（ERG）合成を阻害するデプシペプチド抗真菌物質であり、ペニシリウムから単離されました（IC50 = 34 ng/ml）。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 258871-60-2
Sample solution is provided at 25 µL, 10mM.
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PF-1163B is a depsipeptide antifungal isolated from Penicillium that inhibits ergosterol (ERG) synthesis (IC50 = 34 ng/ml). It inhibits growth of C. albicans (MIC = 32 µg/ml) but not of other Candida strains, A. fumigatus, or HepG2 cells. It acts synergistically with fluconazole to reduce growth of azole-resistant C. albicans (MIC = 2 and 0.0016 µg/ml alone and in combination, respectively). PF-1163B is a hydroxy form of PF-1163A .
Average Rating: 5 (Based on Reviews and 28 reference(s) in Google Scholar.)
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