RGH-5526 (GYKI-11679) (Synonyms: GYKI-11679) |
| カタログ番号GC32606 |
RGH-5526 (GYKI-11679) (GYKI-11679) は新しい降圧剤です。
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Cas No.: 69579-13-1
Sample solution is provided at 25 µL, 10mM.
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GYKI-11679 is a new antihypertensive agent.
GYKI-11679 is a new antihypertensive agent. Results show a sharp (61%) reduction in the hypothalamic Noradrenaline (NA) level 2 h after the administration of 10 mg/kg of GYKI-11679, and this effect lasts for 4 to 6 h. It is demonstrated that GYKI-11679 exerts a greater NA lowering effect in the hypothalamus than in the periphery. GYKI-11679 does not influence the hypothalamic monoamine oxidase (MAO)-activity following prolonged treatment[1].
[1]. Huszti Z, et al. Influence on turnover and level of hypothalamic noradrenaline by a new antihypertensive agent (GYKI 11679). J Neurochem. 1981 Nov;37(5):1272-81.
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