Suc-Leu-Tyr-AMC (Synonyms: SucLYAMC) |
カタログ番号GC44963 |
カルパインは、カルシウム依存性のシステインプロテアーゼのファミリーであり、μ-カルパイン(カルパインI)はマイクロモーラーのカルシウムを必要とし、m-カルパイン(カルパインII)はミリモーラーのカルシウムを必要とします。
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Cas No.: 94367-20-1
Sample solution is provided at 25 µL, 10mM.
The calpains are a family of calcium-dependent cysteine proteases, with calpain I (µ-calpain) requiring micromolar calcium and calpain II (m-calpain) requiring millimolar calcium. Suc-Leu-Tyr-AMC is a fluorescent substrate for calpain I and II and papain (another cysteine protease) that is used for measuring the chymotrypsin-like peptidase activity of the 20S proteasome (excitation max: 360 nm; emission max: 460 nm). Suc-Leu-Tyr-AMC can also be cleaved by the Ti protease from E. coli.
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