TC HSD 21 (Synonyms: TC Hydroxysteroid Dehydrogenase 21) |
| カタログ番号GC13760 |
TC HSD 21 は、14 nM の IC50 を持つ強力な 17β-ヒドロキシステロイド デヒドロゲナーゼ 3 型 (17β-HSD3) 阻害剤です。 TC HSD 21 は、17β-HSD アイソザイムおよび核受容体に対して優れた選択性を示します。
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Cas No.: 330203-01-5
Sample solution is provided at 25 µL, 10mM.
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TC HSD 21 is a potent 17β-hydroxysteroid dehydrogenase type 3 (17β-HSD3) inhibitor with an IC50 of 14 nM. TC HSD 21 shows excellent selectivity over 17β-HSD isoenzymes and nuclear receptors[1].
References:
[1]. Harada K,et al. Identification of oxazolidinediones and thiazolidinediones as potent 17β-hydroxysteroid dehydrogenase type 3 inhibitors. Bioorg Med Chem Lett. 2012 Jan 1;22(1):504-7.
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