Tetromycin B |
カタログ番号GC19001 |
テトロマイシンBは、それぞれrhodesain、falcipain-2、cathepsin L、およびcathepsin Bに対してKi値が0.62、1.42、32.5、および1.59μMのシステインプロテアーゼ阻害剤です。
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Cas No.: 180027-84-3
Sample solution is provided at 25 µL, 10mM.
Tetromycin B is a cysteine protease inhibitor with Ki values of 0.62, 1.42, 32.5, and 1.59 μM for rhodesain, falcipain-2, cathepsin L, and cathepsin B, respectively. It inhibits the growth of T. brucei in vitro (IC50 = 30.87 μM). Tetromycin B is also cytotoxic to HEK293T kidney cells and J774.1 macrophages (IC50s = 71.77 and 20.2 μM, respectively).
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