Tianeptine |
| カタログ番号GC14788 |
非典型的な抗うつ薬
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 66981-73-5
Sample solution is provided at 25 µL, 10mM.
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Tianeptine is a selective facilitator of 5-HT uptake in vitro and in vivo. IC50 Value: N/ATarget: 5-HT ReceptorTianeptine has no affinity for a wide range of receptors, including 5-HT and dopamine (IC50 > 10 μM) and has no effect on noradrenalin or dopamine uptake. Antidepressant, analgesic and neuroprotective following systemic administration in vivo.
References:
[1]. Broqua P; Baudrie V; Chaouloff F Differential effects of the novel antidepressant tianeptine on L-5-hydroxytryptophan (5-HTP)-elicited corticosterone release and body weight loss. Eur Neuropsychopharmacol. 1992 Jun;2(2):115-20.
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