Valbenazine (Synonyms: NBI-98854) |
| カタログ番号GC19370 |
バルベナジン (NBI-98854) は、110 ～ 190 nM の Ki を持つ小胞モノアミン輸送体 2 (VMAT2) 阻害剤です 。
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Cas No.: 1025504-45-3
Sample solution is provided at 25 µL, 10mM.
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Valbenazine is a prodrug of the (+)-α isomer of tetrabenazine for tardive syndrome therapy, and inhibits VMAT2 function.
Valbenazine shows a distinctive improvement in tardive dyskinesia symptoms during the successful Phase II trial[1].
References:
[1]. Müller T, et al. Valbenazine granted breakthrough drug status for treating tardive dyskinesia. Expert Opin Investig Drugs. 2015 Jun;24(6):737-42.
Average Rating: 5 (Based on Reviews and 12 reference(s) in Google Scholar.)
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