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VH 032 amide-alkylC4-acid

カタログ番号GC50544

アルキルリンカーと末端酸を持つVHLリガンド、後方化学反応用

Products are for research use only. Not for human use. We do not sell to patients.

VH 032 amide-alkylC4-acid 化学構造

Cas No.: 2172819-74-6

サイズ 価格 在庫数 個数
25 mg
$336.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC® research and development; incorporates an E3 ligase ligand plus alkylC4 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 - linker 5 PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Zengerle et al (2015) Selective small molecule induced degradation of the BET bromodomain protein BRD4. ACS Chem.Biol. 10 1770 PMID:26035625 |Salami et al (2017) Waste disposal-An attractive strategy for cancer therapy. Science 355 1163 PMID:28302825

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