Reversin 121 |
| カタログ番号GC44821 |
リバーシン121は、P-グリコタンパク質による多剤耐性を逆転させることができる疎水性ペプチド化学感受性体です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 174630-04-7
Sample solution is provided at 25 µL, 10mM.
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Reversin 121 is a hydrophobic peptide chemosensitizer that can reverse P-glycoprotein-mediated multidrug resistance. It binds to the P-glycoprotein multidrug transporter (MDR1) with a Kd value of 77 nM. Reversin 121 modulates P-glycoprotein ATPase activity in Sf9 insect cell membranes expressing human MDR1, plasma membrane vesicles from multidrug-resistant cells, and reconstituted proteoliposomes as well as in a variety of MDR1-expressing intact tumor cells.
Average Rating: 5 (Based on Reviews and 11 reference(s) in Google Scholar.)
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