Riluzole-13C,15N2 |
| カタログ番号GC44842 |
Riluzole-13C、15N2は、GCまたはLC-MSによるリルゾールの定量のための内部標準として使用することを目的としています。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1215552-03-6
Sample solution is provided at 25 µL, 10mM.
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Riluzole-13C,15N2 is intended for use as an internal standard for the quantification of riluzole by GC- or LC-MS. Riluzole is a benzothiazole derivative with anti-excitotoxic effects that acts by blocking the presynaptic release of glutamate, indirectly antagonizing glutamate receptors, and inactivating neuronal voltage-gated Na+ channels (ED50 = 2.3 μM). Riluzole suppresses glutamate-induced seizures in rats at an ED50 value of 3.2 mg/kg and displays neuroprotective effects in hypoxic animals at an ED50 value of 4 mg/kg. Formulations containing riluzole have been explored as therapeutics for slowing disease progression of amyotrophic lateral sclerosis.
Average Rating: 5 (Based on Reviews and 1 reference(s) in Google Scholar.)
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