S1H (trifluoroacetate salt) |
カタログ番号GC90638 |
成長ホルモン受容体の合成ペプチド拮抗剤
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Sample solution is provided at 25 µL, 10mM.
S1H is a synthetic peptide mimetic of human growth hormone amino acids 36-51 and an antagonist of the growth hormone receptor.1 It adopts an α-helical structure in solution and decreases STAT5 phosphorylation induced by human growth hormone in SK-MEL-28 and MALME-3M melanoma cell lines, as well as by prolactin in IM-9 B cell lymphocytes, when used at concentrations of 100 and 200 nM.
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