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Sonelokimab

カタログ番号GC72381

Sonelokimab(ALX 0761;M 1095)は一価ラクダ科動物由来のナノ体からなり、ヒトインターロイキン(IL)−17 A、IL−17 F及びヒト血清アルブミンVHHに特異性を持つ3価ナノ体である。

Products are for research use only. Not for human use. We do not sell to patients.

Sonelokimab 化学構造

Cas No.: 1414386-05-2

サイズ 価格 在庫数 個数
1 mg
$585.00
在庫あり

Tel:(909) 407-4943 Email: sales@glpbio.com


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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
Sonelokimab (ALX 0761; M 1095) is a trivalent nanobody comprised of monovalent camelid-derived nanobodies specific to human interleukin (IL)-17A, IL-17F, and human serum albumin VHHs. Sonelokimab has the potential for plaque-type psoriasis research.

References:
[1]. Kim A Papp, et al. IL17A/F nanobody sonelokimab in patients with plaque psoriasis: a multicentre, randomised, placebo-controlled, phase 2b study. Lancet. 2021 Apr 24;397(10284):1564-1575.
[2]. Martin A Rossotti, et al. Immunogenicity and humanization of single-domain antibodies. FEBS J. 2022 Jul;289(14):4304-4327.

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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