SORT-PGRN interaction inhibitor 1 |
| カタログ番号GC61739 |
SORT-PGRN 相互作用阻害剤 1 は、2 μM の IC50 を持つソルチリン-プログラニュリン相互作用の強力な阻害剤です 。
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Cas No.: 100957-85-5
Sample solution is provided at 25 µL, 10mM.
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SORT-PGRN interaction inhibitor 1 is a potent inhibitor of the sortilin-progranulin interaction with an IC50 of 2 μM[1].
SORT-PGRN interaction inhibitor 1 (Compound 2) with sufficient potency and physicochemical properties to enable co-crystallization with sortilin[1].
[1]. Shawn J Stachel, et al. Identification of potent inhibitors of the sortilin-progranulin interaction. Bioorg Med Chem Lett. 2020 Sep 1;30(17):127403.
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