SPR719 (Synonyms: VXc-486) |
| カタログ番号GC61291 |
SPR719 (VXc-486) は、殺菌活性を持つジャイレース B 阻害剤です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1384984-18-2
Sample solution is provided at 25 µL, 10mM.
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SPR719 (VXc-486) is a gyrase B inhibitor, with bactericidal activity. SPR719 potently inhibits multiple drug-sensitive isolates and drug-resistant isolates of Mycobacterium tuberculosis, with MICs of 0.03 to 0.30 μg/ml and 0.08 to 5.48 μg/ml, respectively[1].
[1]. Locher CP, et al. A novel inhibitor of gyrase B is a potent drug candidate for treatment of tuberculosis and nontuberculosis mycobacterial infections. Antimicrob Agents Chemother. 2015 Mar;59(3):1455-65.
Average Rating: 5 (Based on Reviews and 29 reference(s) in Google Scholar.)
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