SR18662 |
カタログ番号GC39754 |
SR18662 は、4.4 nM の IC50 を持つクルッペル様第 5 因子(KLF5)の強力な阻害剤であり、ML264 の類似体であり、結腸直腸癌細胞に対する阻害効力が改善されています。 SR18662 は、結腸直腸癌の研究に使用できます。
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Cas No.: 2505001-62-5
Sample solution is provided at 25 µL, 10mM.
SR18662 is a potent inhibitor of KrÜppel-like factor five (KLF5) with an IC50 of 4.4 nM, an analogue of ML264 with improved inhibitory potency against colorectal cancer cells. SR18662 can be used for the study of colorectal cancer[1].
[1]. Julie Kim,et al.The Novel Small-Molecule SR18662 Efficiently Inhibits the Growth of Colorectal Cancer In Vitroand In Vivo.Mol Cancer Ther.2019 Nov;18(11):1973-1984.
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