T338C Src-IN-1 |
| カタログ番号GC33168 |
T338C Src-IN-1 は強力な変異型 Src T338C 阻害剤です。 WT c-Src (10 倍の増加) と比較して、T338C の最も強力な阻害 (IC50 = 111 nM) を示しました。
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Cas No.: 1351926-90-3
Sample solution is provided at 25 µL, 10mM.
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T338C Src-IN-1 is a potent mutant-Src T338C inhibitor; exhibited the most potent inhibition of T338C(IC50=111 nM) relative to WT c-Src (10-fold increase).
[1]. Garske AL, et al. Chemical genetic strategy for targeting protein kinases based on covalent complementarity. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15046-52.
Average Rating: 5 (Based on Reviews and 22 reference(s) in Google Scholar.)
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