TFAX 546, SE |
| カタログ番号GC50524 |
黄色蛍光染料；アミン反応性
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Amine reactive yellow fluorescent dye. Insensitive to pH in the range 4 - 10. Forms bright and photostable conjugates with proteins and antibodies. Suitable for use in microscopy. Excitation maximum = 554 nm; emission maximum = 570 nm; extinction coefficient = 112,000 M-1cm-1; quantum yield = 0.79.
Hone et al (2010) Alexa Fluor 546-ArIB[V11L;V16A] is a potent ligand for selectively labeling α 7 nicotinic acetylcholine receptors. J.Neurochem. 114 994 PMID:20492354 |Iwata et al (2005) Increased susceptibility of cytoplasmic over nuclear polyglutamine aggregates to autophagic degradation. Proc.Natl.Acad.Sci.USA. 102 13135 PMID:16141322 |Panchuk-Voloshina et al (1999) Alexa dyes, a series of new fluorescent dyes that yield exceptionally bright, photostable conjugates. J.Histochem.Cytochem. 47 1179 PMID:10449539
| Cas No. | SDF | ||
| Canonical SMILES | ClC(C(Cl)=C1C(O)=O)=C(SCC(NCCCCCC(ON2C(CCC2=O)=O)=O)=O)C(Cl)=C1C(C3=CC4=C(NC(C)(C)CC4C)C(S(=O)([O-])=O)=C3O5)=C6C5=C(S(=O)([O-])=O)C7=[NH+]C(C)(C)CC(C)C7=C6.CC[NH+](CC)CC | ||
| Formula | C44H47Cl3N4O14S.(CH3CH2)3NH | M.Wt | 1159.6 |
| 溶解度 | Soluble in DMSO | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 0.8624 mL | 4.3118 mL | 8.6237 mL |
| 5 mM | 0.1725 mL | 0.8624 mL | 1.7247 mL |
| 10 mM | 0.0862 mL | 0.4312 mL | 0.8624 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 8 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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