TH1834 dihydrochloride |
| カタログ番号GC39303 |
TH1834 二塩酸塩は、特異的な Tip60 (KAT5) ヒストン アセチルトランスフェラーゼ阻害剤です。 TH1834 二塩酸塩はアポトーシスを誘導し、乳がんの DNA 損傷を増加させます。 TH1834 二塩酸塩は、関連するヒストン アセチルトランスフェラーゼ MOF の活性に影響を与えません。抗がん作用。
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Cas No.: 2108830-09-5
Sample solution is provided at 25 µL, 10mM.
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TH1834 dihydrochloride is a specific Tip60 histone acetyltransferase inhibitor. TH1834 dihydrochloride induces apoptosis and increases DNA damage in breast cancer. TH1834 dihydrochloride does not affect the activity of related histone acetyltransferase MOF. Anticancer activity[1].
[1]. Gao C, et al. Rational design and validation of a Tip60 histone acetyltransferase inhibitor. Sci Rep. 2014 Jun 20;4:5372.
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