Thalidomide-NH-C6-NH2 TFA |
| カタログ番号GC39513 |
サリドマイド-NH-C6-NH2 TFA は、サリドマイド ベースのセレブロン リガンドと PROTAC 技術で使用されるリンカーを組み込んだ合成 E3 リガーゼ リガンド-リンカー コンジュゲートです。
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Cas No.: 2093386-51-5
Sample solution is provided at 25 µL, 10mM.
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Thalidomide-NH-C6-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].
[1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163.
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