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Thermopsine (Synonyms: NSC 21725, (-)-Thermopsine)

カタログ番号GC39034

テルモプシンは、Sophora velutina 亜種の果実とさや、および幹の樹皮から分離されたキノリジジン アルカロイドです。

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Thermopsine 化学構造

Cas No.: 486-90-8

サイズ 価格 在庫数 個数
1mg
$66.00
在庫あり
5mg
$161.00
在庫あり
10mg
$239.00
在庫あり
25mg
$403.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description of Thermopsine

Thermopsine is a quinolizidine alkaloid isolated from the fruits and pods and stem bark of Sophora velutina subsp. Thermopsine has antibacterial activity[1].

[1]. Korir E, et al. Quinolizidine alkaloids from Sophora velutina subsp. zimbabweensis (Fabaceae: Sophoreae). Nat Prod Commun. 2012 Aug;7(8):999-1003.

Chemical Properties of Thermopsine

Cas No. 486-90-8 SDF
同義語 NSC 21725, (-)-Thermopsine
Canonical SMILES O=C1C=CC=C2N1C[C@]3([H])[C@@](CCCC4)([H])N4C[C@@]2([H])C3
Formula C15H20N2O M.Wt 244.33
溶解度 DMSO : 25 mg/mL (102.32 mM; Need ultrasonic) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Thermopsine

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 4.0928 mL 20.4641 mL 40.9283 mL
5 mM 0.8186 mL 4.0928 mL 8.1857 mL
10 mM 0.4093 mL 2.0464 mL 4.0928 mL
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計算

In vivo Formulation Calculator (Clear solution) of Thermopsine

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 4 reference(s) in Google Scholar.)

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