Tilfrinib |
| カタログ番号GC40927 |
チルフリニブ (化合物 4f) は、Brk の IC50 値が 3.15 nM である強力かつ選択的な Brk/PTK6 阻害剤です。チルフリニブは良好な抗増殖活性を示し、抗腫瘍の可能性を秘めています。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1600515-49-8
Sample solution is provided at 25 µL, 10mM.
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Tilfrinib is an inhibitor of breast tumor kinase/protein tyrosine kinase 6 (BRK/PTK6; IC50 = 3.15 nM). It is selective for BRK/PTK6 over HER2 (IC50 = 1,300 nM). Tilfrinib inhibits the growth of MCF-7, HS-578/T, and BT-549 breast cancer cells in vitro (GI50s = 0.99, 1.02, and 1.58 μM, respectively).
Average Rating: 5 (Based on Reviews and 22 reference(s) in Google Scholar.)
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