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Timonacic (1,3-Thiazolidine-4-carboxylic acid)

カタログ番号GC34047

チモナク酸 (1,3-チアゾリジン-4-カルボン酸) は、急性および肝障害の治療におけるアジュバントとして使用されます。

Products are for research use only. Not for human use. We do not sell to patients.

Timonacic (1,3-Thiazolidine-4-carboxylic acid) 化学構造

Cas No.: 444-27-9

サイズ 価格 在庫数 個数
10mM (in 1mL DMSO)
$50.00
在庫あり
100mg
$46.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description of Timonacic (1,3-Thiazolidine-4-carboxylic acid)

Timonacic is used as an adjuvant in the treatment of acute and hepatic disorders. It has also been used for the treatment of some cases of cancer, through the induction of the reverse transformation.

[1]. Bakry RS, et al. Spectrophotometric investigation of the formed chelate between timonacic and palladium(II) and its analytical applications. J Pharm Biomed Anal. 1998 May;17(1):95-101.

Chemical Properties of Timonacic (1,3-Thiazolidine-4-carboxylic acid)

Cas No. 444-27-9 SDF
Canonical SMILES O=C(C1NCSC1)O
Formula C4H7NO2S M.Wt 133.17
溶解度 DMSO : 6 mg/mL (45.06 mM) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Timonacic (1,3-Thiazolidine-4-carboxylic acid)

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 7.5092 mL 37.546 mL 75.092 mL
5 mM 1.5018 mL 7.5092 mL 15.0184 mL
10 mM 0.7509 mL 3.7546 mL 7.5092 mL
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**ストックソリューションを準備する際には、常にバイアルラベルおよび MSDS/CoA(オンラインで利用可能)で掲載された製品のロット固有分子量を使用してください。

計算

In vivo Formulation Calculator (Clear solution) of Timonacic (1,3-Thiazolidine-4-carboxylic acid)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Review for Timonacic (1,3-Thiazolidine-4-carboxylic acid)

Average Rating: 5 ★★★★★ (Based on Reviews and 6 reference(s) in Google Scholar.)

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