TMP780 |
| カタログ番号GC62520 |
TMP780 は、13 nM の IC50 を持つ RORγt の逆アゴニストです。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1422053-03-9
Sample solution is provided at 25 µL, 10mM.
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TMP780 is an inverse agonist of RORγt with an IC50 of 13 nM. RORγt is a tractable drug target for the treatment of cutaneous inflammatory disorders[1].
[1]. Skepner J, et al. Pharmacologic inhibition of RORγt regulates Th17 signature gene expression and suppresses cutaneous inflammation in vivo. J Immunol. 2014 Mar 15;192(6):2564-75.
Review for TMP780
Average Rating: 5 (Based on Reviews and 3 reference(s) in Google Scholar.)
Review for TMP780
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