Tpl2 Kinase Inhibitor (Synonyms: c-Cot Kinase Inhibitor, MAP3K8 Kinase Inhibitor, Tumor Progression Locus 2 Kinase Inhibitor) |
カタログ番号GC45067 |
Tpl2 キナーゼ阻害剤 (化合物 1) は、強力かつ選択的な Tpl2 (COT キナーゼ、MAP3K8) 阻害剤であり、炎症反応の調節と一部の癌の進行に重要な役割を果たします。
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Cas No.: 871307-18-5
Sample solution is provided at 25 µL, 10mM.
Tpl2 kinase inhibitor is a reversible inhibitor of tumor progression locus 2 (Tpl2; pIC50 = 7.3). It blocks LPS-induced TNF-α production in mice and human monocytes. Tpl2 kinase inhibitor has been used to evaluate the role of this enzyme in the proliferation and differentiation of cancer cells.
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