Trichostatin C (Synonyms: Antibiotic 145-A) |
カタログ番号GC45080 |
トリコスタチンCは、ヒストンデアセチラーゼを可逆的に阻害する抗真菌性抗生物質であるトリコスタチンAの糖化誘導体です。
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Cas No.: 68676-88-0
Sample solution is provided at 25 µL, 10mM.
Trichostatin C is a glycosylated derivative of trichostatin A , the antifungal antibiotic that reversibly inhibits histone deacetylase. Trichostatin C is reported to be the first example of a glucopyranosyl hydroxamate identified in nature. It has been shown to induce the differentiation of a mouse erythroleukemia cell line and to increase histone H4 acetylation in B cells, though at higher concentrations than trichostatin A.
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