TWIK-1/TREK-1-IN-3 |
| カタログ番号GC71090 |
TWIK-1/TREK-1-IN-3(化合物2h)はtwik関連カリウムチャネル(カリウムチャネル)trek-1の阻害剤である。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1440532-33-1
Sample solution is provided at 25 µL, 10mM.
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TWIK-1/TREK-1-IN-3 (compound 2h) is an inhibitor of TWIK-related potassium channel (Potassium Channel) TREK-1. TREK-1 contains a two-pore domain potassium (K2p) channel that dimerizes into TREK-1 homodimer and TWIK-1/TREK-1 heterodimer, and is an important antidepressant target. TWIK-1/TREK-1-IN-3 targets TREK-1 homodimer and TWIK-1/TREK-1 heterodimer with IC50s of 9.74 μM and 16.5 μM, respectively, and has antidepressant-like effects.
Review for TWIK-1/TREK-1-IN-3
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for TWIK-1/TREK-1-IN-3
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