Tyvelose (Synonyms: D-Tyvelose) |
| カタログ番号GC41225 |
Tyveloseは、寄生性のヘルミンスTの糖タンパク質抗原の免疫優位成分であり、異常な3,6-ジデオキシヘキソース末端糖です。
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Cas No.: 5658/12/8
Sample solution is provided at 25 µL, 10mM.
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Tyvelose is an unusual 3,6-dideoxyhexose terminal sugar and the immunodominant component of glycoprotein antigens in the parasitic helminth T. spiralis, which is responsible for trichinosis in humans. It is produced in high amounts by the infective larva and is immunodominant during the muscle stage of infection. Mice immunized with tyvelose-BSA produce IgG1 antibodies to tyvelose but are not resistant to infection by T. spiralis. Tyvelose-specific antibodies (2.5 mg/20 g) administered to rat pups leads to expulsion of first stage larvae from the intestine within one hour.
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