ULK-101 |
| カタログ番号GC34315 |
ULK-101 は強力で選択的な ULK1 阻害剤であり、ULK1 と ULK2 の IC50 値はそれぞれ 1.6 nM と 30 nM です。 ULK-101 はオートファジーを抑制し、癌細胞を栄養ストレスに敏感にします。
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Cas No.: 2443816-45-1
Sample solution is provided at 25 µL, 10mM.
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ULK-101 is a potent and selective ULK1 inhibitor, with IC50 values of 1.6 nM and 30 nM for ULK1 and ULK2 in vitro, respectively. ULK-101 suppresses autophagy and sensitizes cancer cells to nutrient stress[1].
[1]. Martin KR, et al. A Potent and Selective ULK1 Inhibitor Suppresses Autophagy and Sensitizes Cancer Cells to Nutrient Stress. iScience. 2018 Oct 26;8:74-84.
Average Rating: 5 (Based on Reviews and 22 reference(s) in Google Scholar.)
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